Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2226758 | 0.83 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1PBRM1LMNAHPGD | |
| SCHEMBL2229030 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1PBRM1KDM4ELMNA | |
| SCHEMBL2230343 | 0.74 | PBRM1 (0.37) | ALDH1A1PBRM1KDM4ELMNAHSD17B10 | |
| SCHEMBL2230290 | 0.73 | PBRM1 (0.36) | ALDH1A1PBRM1KDM4ELMNAHSD17B10 | |
| SCHEMBL27855219 | 0.72 | TDP1 (0.36) | SMN1; SMN2ALDH1A1PBRM1KDM4ELMNA | |
| SCHEMBL2847032 | 0.72 | LMNA (0.52) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL27855263 | 0.70 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL3447974 | 0.70 | MIF (0.43) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL27855255 | 0.69 | TSHR (0.33) | TSHR | |
| SCHEMBL2229704 | 0.69 | MAPT (0.35) | SMN1; SMN2ALDH1A1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091346-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2011-07-28 | — | — | WO | disclosed |