SCHEMBL2226909

SCHEMBL2226909

C=CCc1ccc(OOC)c(OC)c1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.80
PPARA Q07869 3/20 0.80
PPARG P37231 1/20 0.80
PPARD Q03181 1/20 0.80
PTGS1 P23219 2/20 0.63
CYP3A4 P08684 3/20 0.63
ALOX5 P09917 2/20 0.63
AR P10275 1/20 0.63
TRPM8 Q7Z2W7 1/20 0.63
SMN1; SMN2 Q16637 5/20 0.61
MAPT P10636 4/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
LMNA P02545 2/20 0.61
GAA P10253 2/20 0.61
KDM4E B2RXH2 1/20 0.61
HTT P42858 1/20 0.61
TDP1 Q9NUW8 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
GABRA1 P14867 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4353980 0.93 ALDH1A1 (0.86) ALDH1A1PPARAPPARGPPARDPTGS1
Methyleugenol SCHEMBL29376951 0.89 ALDH1A1 (1.00) ALDH1A1PPARAPPARGPPARDPTGS1
Methyleugenol SCHEMBL113794 0.89 ALDH1A1 (1.00) ALDH1A1PPARAPPARGPPARDPTGS1
Methyleugenol SCHEMBL1869396 0.89 ALDH1A1 (1.00) ALDH1A1PPARAPPARGPPARDPTGS1
Phenol SCHEMBL15272898 0.89 ALDH1A1 (0.63) ALDH1A1PPARAPPARGPPARDPTGS1
Methyleugenol SCHEMBL5564539 0.87 ALDH1A1 (0.96) ALDH1A1PPARAPPARGPPARDPTGS1
Methyleugenol SCHEMBL27951383 0.87 ALDH1A1 (0.96) ALDH1A1PPARAPPARGPPARDPTGS1
Methyleugenol SCHEMBL27600712 0.87 ALDH1A1 (0.96) ALDH1A1PPARAPPARGPPARDPTGS1
SCHEMBL28143551 0.87 ALDH1A1 (0.75) ALDH1A1PPARAPPARGPPARDPTGS1
SCHEMBL1870530 0.86 ALDH1A1 (0.86) ALDH1A1PPARAPPARGPPARDPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117947065-A Construction method and application of engineering strain for producing methoxy eugenol 江苏省中国科学院植物研究所 2024-04-30 CN claimed
US-20230416289-A1 METHODS FOR ELECTROREDUCTIVE LIGNIN DEPOLYMERIZATION BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2023-12-28 US claimed
US-11267838-B2 Methods for lignin depolymerization using thiols BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2022-03-08 US claimed
CN-103874432-B Molecularly imprinted polymers for treating tobacco material and filtering smoke from smoking articles R·J·雷诺兹烟草公司 2021-03-19 CN claimed
EP-3022281-B1 PROCESS FOR REDUCING ETHANOL LOSS WHILE DEVELOPING DESIRABLE ORGANOLEPTICS DURING WOODEN BARREL AGING OF ALCOHOLIC BEVERAGE CRYOVAC LLC (US) 2020-03-11 EP claimed
US-10561168-B2 Tobacco-derived components and materials R.J. REYNOLDS TOBACCO COMPANY (US) 2020-02-18 US claimed
US-20200048292-A1 METHODS FOR LIGNIN DEPOLYMERIZATION USING THIOLS UNITED STATES DEPARTMENT OF ENERGY 2020-02-13 US claimed
CN-105593356-B Method for reducing ethanol loss while creating desirable organoleptic properties during wooden barrel aging of alcoholic beverages 克里奥瓦克公司 2020-01-07 CN claimed
WO-2018195000-A1 METHODS FOR LIGNIN DEPOLYMERIZATION USING THIOLS BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2018-10-25 WO claimed
US-9944891-B2 Process for reducing ethanol loss while developing desirable organoleptics during wooden barrel aging of alcoholic beverage CRYOVAC, INC. (US) 2018-04-17 US claimed
US-8955523-B2 Tobacco-derived components and materials R.J. REYNOLDS TOBACCO COMPANY (US) 2015-02-17 US claimed
US-20150037459-A1 Process for Reducing Ethanol Loss While Developing Desirable Organoleptics During Wooden Barrel Aging of Alcoholic Beverage CRYOVAC, INC. 2015-02-05 US claimed
WO-2015010015-A2 PROCESS FOR REDUCING ETHANOL LOSS WHILE DEVELOPING DESIRABLE ORGANOLEPTICS DURING WOODEN BARREL AGING OF ALCOHOLIC BEVERAGE CRYOVAC, INC. (US) 2015-01-22 WO claimed
EP-2709476-A2 MOLECULARLY IMPRINTED POLYMERS FOR TREATING TOBACCO MATERIAL AND FILTERING SMOKE FROM SMOKING ARTICLES R. J. Reynolds Tobacco Company (US) 2014-03-26 EP claimed
EP-2523568-B1 TOBACCO-DERIVED COMPONENTS AND MATERIALS REYNOLDS TOBACCO CO R (US) 2013-12-18 EP claimed
US-20130014771-A1 TOBACCO-DERIVED COMPONENTS AND MATERIALS R. J. REYNOLDS TOBACCO COMPANY 2013-01-17 US claimed
US-20120291793-A1 MOLECULARLY IMPRINTED POLYMERS FOR TREATING TOBACCO MATERIAL AND FILTERING SMOKE FROM SMOKING ARTICLES R.J. REYNOLDS TOBACCO COMPANY 2012-11-22 US claimed
WO-2012158915-A2 MOLECULARLY IMPRINTED POLYMERS FOR TREATING TOBACCO MATERIAL AND FILTERING SMOKE FROM SMOKING ARTICLES R. J. REYNOLDS TOBACCO COMPANY (US) 2012-11-22 WO claimed
EP-2523568-A2 TOBACCO-DERIVED COMPONENTS AND MATERIALS R. J. Reynolds Tobacco Company (US) 2012-11-21 EP claimed
WO-2011088171-A2 TOBACCO-DERIVED COMPONENTS AND MATERIALS R. J. REYNOLDS TOBACCO COMPANY (US) 2011-07-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11267838-B2 Methods for lignin depolymerization using thiols DCXR, GLO1, LOX ALDH1A1 454/4885PPARA 3093/4885PPARG 3767/4885
US-20200048292-A1 METHODS FOR LIGNIN DEPOLYMERIZATION USING THIOLS DCXR, GLO1, LOX ALDH1A1 454/4885PPARA 3093/4885PPARG 3767/4885
US-20230416289-A1 METHODS FOR ELECTROREDUCTIVE LIGNIN DEPOLYMERIZATION DCXR, LOX, ENGASE ALDH1A1 471/4885PPARA 3729/4885PPARG 4269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.