Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | TNF | P01375 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19205595 | 0.86 | KCNJ5 (0.42) | TRPV1 | |
| SCHEMBL19205594 | 0.86 | KCNJ5 (0.42) | TRPV1 | |
| SCHEMBL19205808 | 0.78 | RORC (0.39) | — | |
| SCHEMBL19205809 | 0.78 | RORC (0.39) | — | |
| SCHEMBL21796351 | 0.77 | TRPV1 (0.40) | TRPV1TRPV4 | |
| SCHEMBL19205763 | 0.77 | TRPV1 (0.40) | TRPV1TRPV4 | |
| SCHEMBL22270887 | 0.75 | KDM4E (0.40) | TRPV1PTGDR2 | |
| SCHEMBL19205684 | 0.75 | RORC (0.44) | — | |
| SCHEMBL19205807 | 0.75 | RORC (0.44) | — | |
| SCHEMBL19205643 | 0.75 | RORC (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |