Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18449672 | 0.85 | KMT2A (0.47) | LMNAKMT2AMAPTHTTL3MBTL1 | |
| SCHEMBL18448782 | 0.82 | CYP19A1 (0.54) | LMNAKMT2AMAPTIDO1MEN1 | |
| SCHEMBL18484534 | 0.79 | KMT2A (0.43) | LMNAKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL18448548 | 0.78 | ALDH1A1 (0.51) | LMNAMAPTHTTL3MBTL1GABRA5 | |
| SCHEMBL28632021 | 0.77 | MEN1 (0.46) | LMNAKMT2AMAPTHTTL3MBTL1 | |
| SCHEMBL5797839 | 0.76 | ALDH1A1 (0.57) | KMT2AMAPTL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL28642927 | 0.75 | ALDH1A1 (0.40) | LMNAKMT2AMAPTHTTMEN1 | |
| SCHEMBL18447793 | 0.75 | CYP11B1 (0.56) | MAPTIDO1ALDH1A1CNR2 | |
| SCHEMBL18449560 | 0.75 | IDO1 (0.50) | KMT2AMAPTHTTL3MBTL1IDO1 | |
| SCHEMBL18448565 | 0.74 | KMT2A (0.43) | LMNAKMT2AMAPTHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |