Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18449672 | 0.89 | KMT2A (0.47) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL28627402 | 0.84 | S1PR4 (0.43) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL18447793 | 0.84 | CYP11B1 (0.56) | MAPTALDH1A1IDO1CYP11B1CYP11B2 | |
| SCHEMBL18448787 | 0.83 | CYP11B1 (0.39) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL28642927 | 0.79 | ALDH1A1 (0.40) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL18447815 | 0.79 | HPGD (0.47) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL22270628 | 0.77 | LMNA (0.44) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL18448782 | 0.76 | CYP19A1 (0.54) | MEN1KMT2AMAPTLMNAIDO1 | |
| SCHEMBL19205613 | 0.74 | ADRA2A (0.41) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL19205615 | 0.74 | ADRA2A (0.41) | MEN1KMT2AMAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026050-B | Novel compounds as ROR gamma modulators | 格兰马克药品股份有限公司 | 2021-04-30 | — | — | CN | disclosed |