Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | GCG | P01275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19205663 | 0.87 | SOS1 (0.39) | SOS1MAPK14LMNATP53P2RX7 | |
| SCHEMBL19205662 | 0.87 | SOS1 (0.39) | SOS1MAPK14LMNATP53P2RX7 | |
| SCHEMBL19205805 | 0.83 | TAAR1 (0.39) | SOS1GCGRMAPK14LMNATP53 | |
| SCHEMBL19205804 | 0.83 | TAAR1 (0.39) | SOS1GCGRMAPK14LMNATP53 | |
| SCHEMBL19205809 | 0.76 | RORC (0.39) | MAPK14 | |
| SCHEMBL19205808 | 0.76 | RORC (0.39) | MAPK14 | |
| SCHEMBL22270677 | 0.76 | ATP1A1 (0.43) | LMNAPTGDR2 | |
| SCHEMBL22270670 | 0.74 | DYRK1A (0.43) | SOS1LMNATP53 | |
| SCHEMBL18485915 | 0.74 | PIK3CD (0.36) | APPTP53PIK3CD | |
| SCHEMBL19205789 | 0.74 | SOS1 (0.41) | SOS1MAPK14PIK3CDEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |