Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2793544 | 0.79 | HTR2A (0.41) | HTR2AHTR2CMEN1HDAC9TSHR | |
| SCHEMBL11488652 | 0.79 | HTR2A (0.43) | HTR2AHTR2CMEN1TSHRDRD2 | |
| SCHEMBL28831342 | 0.78 | KDM1A (0.41) | HTR2AHTR2CMEN1HDAC9PNMT | |
| SCHEMBL28826900 | 0.76 | HTR2A (0.39) | HTR2AHTR2CMEN1HDAC9PNMT | |
| SCHEMBL27928027 | 0.76 | HTR2A (0.39) | HTR2AHTR2CMEN1HDAC9PNMT | |
| SCHEMBL9374419 | 0.76 | CYP3A4 (0.42) | HTR2AMEN1HDAC9KMT2ACYP3A4 | |
| SCHEMBL27928025 | 0.76 | HTR2A (0.39) | HTR2AHTR2CMEN1HDAC9PNMT | |
| Hydrochloric Acid SCHEMBL6021932 | 0.75 | CYP3A4 (0.41) | HTR2AMEN1HDAC9KMT2ACYP3A4 | |
| SCHEMBL30821544 | 0.74 | HTR2A (0.37) | HTR2AHTR2CMEN1HDAC9PNMT | |
| SCHEMBL28008899 | 0.74 | ALDH1A1 (0.39) | HTR2AHTR2CMEN1HDAC9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011086003-A1 | PROCESS FOR THE PREPARATION OF SOLIFENACIN AND SOLIFENACIN SUCCINATE | ZAKLADY FARMACEUTYCZNE POLPHARMA SA (PL) | 2011-07-21 | — | — | WO | disclosed |