Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5199073 | 0.86 | HTR2A (0.40) | HTR2AHTR2CMEN1KDM1ATSHR | |
| SCHEMBL2227079 | 0.79 | HTR2A (0.40) | HTR2AHTR2CMAOBPNMTCD44 | |
| SCHEMBL27426212 | 0.78 | CACNB4 (0.38) | — | |
| SCHEMBL27901779 | 0.76 | HTR2A (0.38) | HTR2AHTR2CMAOBPNMTCD44 | |
| SCHEMBL24710630 | 0.75 | MAOB (0.43) | HTR2AHTR2CMAOBPNMTCD44 | |
| SCHEMBL5550987 | 0.75 | HTR2A (0.43) | HTR2AHTR2CMAOBPNMTCD44 | |
| SCHEMBL29674233 | 0.75 | HTR2A (0.47) | HTR2AHTR2CMAOBPNMTCD44 | |
| SCHEMBL29674239 | 0.75 | HTR2A (0.43) | HTR2AHTR2CMAOBPNMTCD44 | |
| SCHEMBL22541598 | 0.75 | HTR2A (0.47) | HTR2AHTR2CMAOBPNMTCD44 | |
| SCHEMBL327743 | 0.75 | HTR2A (0.43) | HTR2AHTR2CMAOBPNMTCD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228170-A | INHIBITOR OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE | SMITHKLINE CORPORATION (US) | 1980-10-14 | — | — | US | disclosed |