SCHEMBL2227182

SCHEMBL2227182

O=C(O)C1=CN2CC=CC=C2N=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10077278 0.72
SCHEMBL10078203 0.71
SCHEMBL1008140 0.71
Hydrochloric Acid SCHEMBL16973350 0.70
SCHEMBL5391649 0.66
SCHEMBL15758640 0.65
SCHEMBL207504 0.63
SCHEMBL2301140 0.63
SCHEMBL31287283 0.63
Hydrochloric Acid SCHEMBL7615185 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011089457-A1 NOVEL MEDICINAL COMPOUNDS URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) 2011-07-28 WO disclosed
US-4452982-A Process for the preparation of nitrogen-bridgehead condensed pyrimidine compounds, and pharmaceutical compositions containing them CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) 1984-06-05 US disclosed
US-4234586-A ASTHMA; 9-HYDRAZONO-4H-PYRIDO(1,2A)PYRIMIDINE DERIVATIVES CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1980-11-18 US disclosed