Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.44 |
| ▸ | CCR9 | P51686 | 5/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2225526 | 0.85 | SLC40A1 (0.50) | SLC40A1CCR2MEN1KMT2AGLO1 | |
| SCHEMBL3535998 | 0.81 | NFE2L2 (0.61) | SLC40A1GLO1KDM1A | |
| SCHEMBL3535146 | 0.80 | SLC40A1 (0.61) | SLC40A1MEN1KMT2AGLO1PIK3CD | |
| SCHEMBL12096791 | 0.79 | HSD17B2 (0.46) | CCR9MEN1KMT2AGLO1HSD17B2 | |
| SCHEMBL1444444 | 0.79 | HSD17B2 (0.44) | CCR9CCR2HSD17B2 | |
| SCHEMBL3530032 | 0.77 | APP (0.42) | SLC40A1PIK3CD | |
| SCHEMBL12096937 | 0.76 | HSD17B2 (0.52) | SLC40A1MEN1KMT2AHSD17B2 | |
| SCHEMBL12096762 | 0.75 | PTGES2 (0.43) | SLC40A1CCR2MEN1KMT2AHSD17B2 | |
| SCHEMBL3533105 | 0.74 | SLC40A1 (0.55) | SLC40A1CCR9KMT2AGLO1 | |
| SCHEMBL1714365 | 0.74 | MEN1 (0.53) | SLC40A1CCR2MEN1KMT2AHSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011086307-A1 | PYRROLOPYRIDINE DERIVATIVES AS NURR1 ACTIVATORS USEFUL FOR TREATING PARKINSON'S DISEASE | LABORATOIRES FOURNIER S.A. (FR) | 2011-07-21 | — | — | WO | disclosed |