Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 19/20 | 0.60 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.55 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.55 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | HCK | P08631 | 3/20 | 0.44 |
| ▸ | SRC | P12931 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.44 |
| ▸ | MTOR | P42345 | 3/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.44 |
| ▸ | PRKDC | P78527 | 3/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037 | 0.91 | PIK3CD (0.72) | PIK3CDPIK3CGCSNK1EPIK3R1ABL1 | |
| SCHEMBL29651742 | 0.91 | PIK3CD (0.72) | PIK3CDPIK3CGCSNK1EPIK3R1ABL1 | |
| SCHEMBL130432 | 0.90 | PIK3CD (0.60) | PIK3CDPIK3CGCSNK1EPIK3R1ABL1 | |
| SCHEMBL29651830 | 0.90 | PIK3CD (0.60) | PIK3CDPIK3CGCSNK1EPIK3R1ABL1 | |
| SCHEMBL22275994 | 0.86 | PIK3CD (0.70) | PIK3CDPIK3CGCSNK1EPIK3R1ABL1 | |
| SCHEMBL29651659 | 0.86 | PIK3CD (0.72) | PIK3CDPIK3CGCSNK1EPIK3R1ABL1 | |
| SCHEMBL10807 | 0.86 | PIK3CD (0.72) | PIK3CDPIK3CGCSNK1EPIK3R1ABL1 | |
| SCHEMBL11258 | 0.83 | PIK3CD (0.58) | PIK3CDPIK3CGCSNK1EPIK3R1ABL1 | |
| SCHEMBL29651774 | 0.83 | PIK3CD (0.58) | PIK3CDPIK3CGCSNK1EPIK3R1ABL1 | |
| SCHEMBL15582861 | 0.81 | PIK3CD (0.72) | PIK3CDPIK3CGCSNK1EPIK3R1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239427-A1 | NOVEL KINASE MODULATORS | RHIZEN PHARMACEUTICALS AG (CH) | 2020-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239427-A1 | NOVEL KINASE MODULATORS | PRKCA, PRKCH, PRKCB | PIK3CD 70/4885PIK3CG 99/4885CSNK1E 109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.