Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22276876 | 0.91 | SMN1; SMN2 (0.47) | NPC1RAB9AKMT2AMEN1PIK3CG | |
| SCHEMBL31286070 | 0.79 | KDM4E (0.44) | NPC1RAB9AHPGDCYP1A2CYP2D6 | |
| SCHEMBL22276854 | 0.79 | KDM4E (0.44) | NPC1RAB9AHPGDCYP1A2CYP2D6 | |
| SCHEMBL22280605 | 0.79 | NPC1 (0.45) | NPC1RAB9AHPGDCYP1A2CYP2D6 | |
| SCHEMBL25069991 | 0.74 | KDM4E (0.45) | NPC1RAB9AHPGDCYP1A2CYP2D6 | |
| SCHEMBL25069997 | 0.74 | PIK3CG (0.37) | NPC1RAB9AKMT2AMEN1PIK3CG | |
| SCHEMBL25070384 | 0.74 | PIK3CG (0.37) | NPC1RAB9AKMT2AMEN1PIK3CG | |
| SCHEMBL10085362 | 0.69 | PIK3CG (0.76) | NPC1RAB9AHPGDCYP1A2CYP2D6 | |
| SCHEMBL22276872 | 0.69 | PIK3CG (0.43) | PIK3CGMAPTTP53 | |
| SCHEMBL25401997 | 0.69 | MEN1 (0.65) | KMT2AMEN1MAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230058950-A1 | UREA COMPOUND HAVING SUBSTITUENT | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-02-23 | — | — | US | disclosed |
| EP-3915558-A1 | SUBSTITUENT-INCLUDING UREA COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2021-12-01 | — | — | EP | disclosed |
| WO-2020153433-A1 | SUBSTITUENT-INCLUDING UREA COMPOUND | 第一三共株式会社 | 2020-07-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230058950-A1 | UREA COMPOUND HAVING SUBSTITUENT | SIRT6, SIRT1, SIRT2 | NPC1 1240/4885RAB9A 3232/4885HPGD 1718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.