Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 9/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2203254 | 0.84 | L3MBTL3 (0.46) | UGCGL3MBTL3L3MBTL1 | |
| SCHEMBL2231585 | 0.83 | TACR1 (0.40) | TACR1GPBAR1CYP3A4SIGMAR1PDE4D | |
| Hydrochloric Acid SCHEMBL2227825 | 0.81 | KMT2A (0.39) | TACR1GPBAR1L3MBTL3L3MBTL1MAPT | |
| SCHEMBL2227154 | 0.79 | FFAR4 (0.38) | UGCGTACR1 | |
| SCHEMBL2230182 | 0.77 | TACR1 (0.42) | TACR1POLB | |
| SCHEMBL2229019 | 0.73 | TACR1 (0.40) | TACR1POLB | |
| SCHEMBL2203140 | 0.71 | ALKBH5 (0.49) | ARL3MBTL1MAPTPDE4DPOLB | |
| SCHEMBL2201747 | 0.70 | KMT2A (0.47) | L3MBTL3L3MBTL1POLB | |
| SCHEMBL2199963 | 0.70 | PDE4D (0.62) | GPR119L3MBTL1PDE4D | |
| SCHEMBL2201429 | 0.69 | KMT2A (0.46) | L3MBTL3L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977358-B2 | Pyrazol derivatives | HOFFMANN-LA ROCHE INC. (US) | 2011-07-12 | — | — | US | disclosed |