Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22277242 | 0.93 | CNR2 (0.40) | KDM1ANAAAPRMT5GABRA1GABRB2 | |
| SCHEMBL22277711 | 0.89 | FFAR4 (0.35) | NAAAPRMT5GABRA1GABRB2ERN1 | |
| SCHEMBL22277552 | 0.89 | KDM1A (0.35) | KDM1ANAAAPRMT5GABRA1GABRB2 | |
| SCHEMBL22277640 | 0.89 | MAPT (0.36) | KDM1AGABRA1GABRB2KDM4ENPC1 | |
| SCHEMBL22277487 | 0.88 | FFAR4 (0.40) | GABRA1GABRB2KDM4ENPC1ALDH1A1 | |
| SCHEMBL15681400 | 0.87 | KDM1A (0.35) | KDM1AGABRA1GABRB2FPR2FFAR4 | |
| SCHEMBL22277430 | 0.86 | FFAR4 (0.37) | KDM1AGABRA1GABRB2FPR2FFAR4 | |
| SCHEMBL20803734 | 0.86 | KDM1A (0.42) | KDM1ANAAAGABRA1GABRB2FPR2 | |
| SCHEMBL22269483 | 0.86 | KDM1A (0.34) | KDM1AGABRA1GABRB2FPR2FFAR4 | |
| SCHEMBL17487751 | 0.85 | FFAR4 (0.34) | PRMT5FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239775-A1 | TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |