Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | GYS1 | P13807 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22277212 | 0.93 | FFAR4 (0.41) | FFAR4MRGPRX4HRH3RAB9AGABRA1 | |
| SCHEMBL15681400 | 0.91 | KDM1A (0.35) | FFAR4GABRA1GABRB2 | |
| SCHEMBL22277430 | 0.90 | FFAR4 (0.37) | FFAR4GABRA1GABRB2 | |
| SCHEMBL22269483 | 0.90 | KDM1A (0.34) | FFAR4GABRA1GABRB2 | |
| SCHEMBL22277562 | 0.89 | FFAR4 (0.38) | FFAR4MRGPRX4HRH3GYS1KDM4E | |
| SCHEMBL22277640 | 0.88 | MAPT (0.36) | KDM4ENPC1ALDH1A1MAPTHPGD | |
| SCHEMBL22277485 | 0.88 | KDM1A (0.38) | FFAR4KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL16071781 | 0.88 | FFAR4 (0.43) | FFAR4MRGPRX4HRH3KDM4ENPC1 | |
| SCHEMBL22277436 | 0.87 | KDM1A (0.33) | FFAR4GABRA1GABRB2 | |
| SCHEMBL12760157 | 0.87 | FFAR4 (0.33) | FFAR4GYS1KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239775-A1 | TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |