Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 4/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | TACR2 | P21452 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22277651 | 0.93 | MAPT (0.34) | MAPTKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL9925076 | 0.89 | MAPT (0.33) | MAPTKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL22277485 | 0.89 | KDM1A (0.38) | MAPTKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL22277487 | 0.88 | FFAR4 (0.40) | MAPTKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL12760320 | 0.87 | KDM4E (0.31) | MAPTKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL12760342 | 0.87 | KDM4E (0.31) | MAPTKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL22269483 | 0.87 | KDM1A (0.34) | KDM1AGABRA1GABRB2 | |
| SCHEMBL12769247 | 0.87 | SLC6A2 (0.34) | KDM1ASLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL22277601 | 0.87 | FFAR4 (0.34) | KDM1AGABRA1GABRB2 | |
| SCHEMBL9924995 | 0.87 | KDM1A (0.34) | MAPTKDM4EALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239775-A1 | TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |