Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22277320 | 0.94 | HPGD (0.38) | HPGDLMNAALOX15SPHK1PDE5A | |
| SCHEMBL22277313 | 0.91 | HPGD (0.39) | HPGDLMNAALOX15SMN1; SMN2CYP3A4 | |
| SCHEMBL22277665 | 0.89 | HPGD (0.38) | HPGDLMNAALOX15SMN1; SMN2FFAR4 | |
| SCHEMBL22277622 | 0.88 | HPGD (0.37) | HPGDLMNAALOX15SPHK1SMN1; SMN2 | |
| SCHEMBL15723220 | 0.87 | HPGD (0.34) | HPGDSPHK1FFAR4SLC6A3 | |
| SCHEMBL22277664 | 0.87 | SPHK1 (0.45) | SPHK1 | |
| SCHEMBL10416710 | 0.83 | AOC3 (0.36) | LMNAALOX15SPHK1FFAR4SLC6A3 | |
| SCHEMBL10416709 | 0.83 | AOC3 (0.36) | LMNAALOX15SPHK1FFAR4SLC6A3 | |
| SCHEMBL22277662 | 0.83 | HPGD (0.38) | HPGDLMNAALOX15SMN1; SMN2FFAR4 | |
| SCHEMBL9925050 | 0.83 | F2 (0.35) | USP2FFAR4MEN1KMT2ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239775-A1 | TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |