Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22277665 | 0.90 | HPGD (0.38) | HPGDLMNAALOX15FFAR4F2 | |
| SCHEMBL22277608 | 0.88 | HPGD (0.38) | HPGDLMNAALOX15FFAR4CCR5 | |
| SCHEMBL22277328 | 0.86 | HPGD (0.39) | HPGDLMNAALOX15SMN1; SMN2KMT2A | |
| SCHEMBL22277313 | 0.86 | HPGD (0.39) | HPGDLMNAALOX15CCR5CYP3A4 | |
| SCHEMBL22277322 | 0.86 | FFAR4 (0.35) | HPGDFFAR4F2KMT2AALDH1A1 | |
| SCHEMBL22277662 | 0.84 | HPGD (0.38) | HPGDLMNAALOX15FFAR4SMN1; SMN2 | |
| SCHEMBL22277320 | 0.82 | HPGD (0.38) | HPGDLMNAALOX15FFAR4SMN1; SMN2 | |
| SCHEMBL15723220 | 0.82 | HPGD (0.34) | HPGDFFAR4F2SPHK1 | |
| SCHEMBL17017051 | 0.81 | HPGD (0.44) | HPGDLMNAALOX15SMN1; SMN2GLA | |
| SCHEMBL12197152 | 0.81 | HPGD (0.36) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239775-A1 | TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |