SCHEMBL22277666

SCHEMBL22277666

C/C=C/CCc1ccc(C2CCC(C3CCC(CCc4ccc(OCCCC)c(F)c4F)CC3)CC2)cc1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 12/20 0.34
KCNH2 Q12809 2/20 0.33
FFAR4 Q5NUL3 1/20 0.32
SPHK2 Q9NRA0 7/20 0.31
AOC3 Q16853 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22277772 0.95 FFAR4 (0.35) SPHK1KCNH2FFAR4SPHK2
SCHEMBL22277652 0.93 SPHK1 (0.34) SPHK1FFAR4SPHK2
SCHEMBL22277621 0.93 AOC3 (0.32) SPHK1KCNH2FFAR4AOC3
SCHEMBL22277770 0.91 ALOX5 (0.34) SPHK1KCNH2
SCHEMBL22277614 0.90 SPHK1 (0.35) SPHK1KCNH2SPHK2
SCHEMBL22277740 0.90 SPHK1 (0.38) SPHK1KCNH2FFAR4SPHK2
SCHEMBL22277533 0.89 SPHK1 (0.45) SPHK1KCNH2FFAR4SPHK2
SCHEMBL22277670 0.89 SPHK1 (0.42) SPHK1SPHK2AOC3
SCHEMBL22277682 0.88 SPHK1 (0.35) SPHK1SPHK2AOC3
SCHEMBL22277623 0.88 ALOX5 (0.35) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200239775-A1 TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2020-07-30 US disclosed