SCHEMBL2227779

SCHEMBL2227779

O=C1C=CC2=C(C1)Oc1cc(O)ccc1C2c1ccccc1C(=O)O.[NaH].[NaH]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.47
ALDH1A1 P00352 6/20 0.40
HSD17B10 Q99714 5/20 0.40
HPGD P15428 3/20 0.40
BRCA1 P38398 2/20 0.40
CYP3A4 P08684 2/20 0.40
ALOX15 P16050 2/20 0.40
ALOX12 P18054 2/20 0.40
CASP1 P29466 1/20 0.40
STAT6 P42226 1/20 0.40
CASP7 P55210 1/20 0.40
HBB P68871 1/20 0.40
HIF1A Q16665 1/20 0.40
ESR2 Q92731 3/20 0.39
ESR1 P03372 3/20 0.39
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
USP2 O75604 3/20 0.39
MAPT P10636 3/20 0.39
THRB P10828 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL381409 0.99 CYP2C9 (0.48) CYP2C9ALDH1A1HSD17B10HPGDBRCA1
SCHEMBL21635716 0.86 ALDH1A1 (0.38) CYP2C9ALDH1A1HSD17B10HPGDBRCA1
SCHEMBL7759506 0.86 ALDH1A1 (0.39) CYP2C9ALDH1A1HSD17B10HPGDBRCA1
SCHEMBL5468852 0.85 MEN1 (0.53) ALDH1A1HSD17B10HPGDALOX15ALOX12
SCHEMBL7578109 0.84 ESR1 (0.37) CYP2C9ALDH1A1HSD17B10HPGDBRCA1
SCHEMBL12495911 0.83 RXFP1 (0.38) CYP2C9ESR2ESR1MEN1KMT2A
Hydrochloric Acid SCHEMBL584413 0.82 RXFP1 (0.38) CYP2C9ESR2ESR1MEN1KMT2A
Fluorescin SCHEMBL1938032 0.82 CYP2C9 (0.69) CYP2C9ALDH1A1HSD17B10HPGDBRCA1
Sulfuric Acid SCHEMBL592953 0.81 CYP2C9 (0.41) CYP2C9ALDH1A1HSD17B10ALOX15CASP1
Fluorescin SCHEMBL27403 0.80 CYP2C9 (0.71) CYP2C9ALDH1A1HSD17B10HPGDBRCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011089571-A2 A COSMETIC COMPOSITION INCLUDING AT LEAST ONE FLUOROPHORE COMPOUND L'OREAL (FR) 2011-07-28 WO disclosed