SCHEMBL5468852

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15346153	0.87	CYP2C9 (0.39)	MEN1KMT2AMAPTTHRBUSP2
	SCHEMBL381409	0.86	CYP2C9 (0.48)	MEN1KMT2AMAPTTHRBUSP2
	SCHEMBL2227779	0.85	CYP2C9 (0.47)	MEN1KMT2AMAPTTHRBUSP2
	SCHEMBL7578109	0.79	ESR1 (0.37)	MEN1KMT2AMAPTTHRBUSP2
	SCHEMBL12495911	0.78	RXFP1 (0.38)	MEN1KMT2AMAPTTHRBUSP2
	SCHEMBL7759506	0.78	ALDH1A1 (0.39)	MEN1KMT2AMAPTTHRBUSP2
	Hydrochloric Acid SCHEMBL584413	0.77	RXFP1 (0.38)	MEN1KMT2AMAPTTHRBUSP2
	SCHEMBL24148895	0.77	MEN1 (0.59)	MEN1KMT2AMAPTTHRBUSP2
	SCHEMBL21635716	0.76	ALDH1A1 (0.38)	MEN1KMT2AMAPTTHRBUSP2
	SCHEMBL5472358	0.76	MAOB (0.39)	MEN1KMT2AMAPTTHRBUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.