Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228257 | 0.79 | ALDH1A1 (0.41) | ALDH1A1SGMS2MAPTHTTMEN1 | |
| SCHEMBL2226921 | 0.79 | ALDH1A1 (0.39) | ALDH1A1SGMS2MAPTHTTMEN1 | |
| SCHEMBL2228853 | 0.72 | ALDH1A1 (0.40) | ALDH1A1SGMS2MAPTHTTMEN1 | |
| SCHEMBL19334515 | 0.70 | MAPT (0.50) | ALDH1A1MAPTHTTGAALMNA | |
| SCHEMBL1826516 | 0.70 | MAPT (0.61) | ALDH1A1MAPTHTTMEN1GAA | |
| SCHEMBL5982504 | 0.70 | MAPT (0.61) | ALDH1A1MAPTHTTMEN1GAA | |
| SCHEMBL2230721 | 0.69 | SIGMAR1 (0.46) | ALDH1A1HTTMEN1KMT2ANPSR1 | |
| SCHEMBL2230290 | 0.68 | PBRM1 (0.36) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL7156936 | 0.67 | HTT (0.42) | ALDH1A1SGMS2MAPTHTTMEN1 | |
| SCHEMBL9141059 | 0.67 | ALDH1A1 (0.51) | ALDH1A1SGMS2MAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091346-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2011-07-28 | — | — | WO | disclosed |