Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15499521 | 0.73 | NPSR1 (0.48) | NPSR1ALDH1A1RAB9AMAPTMAPK1 | |
| SCHEMBL4971176 | 0.71 | ALDH1A1 (0.54) | NPSR1ALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL2565693 | 0.71 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1KMT2AMEN1GAA | |
| SCHEMBL138432 | 0.70 | NPSR1 (0.50) | NPSR1ALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL11862805 | 0.70 | NPSR1 (0.56) | NPSR1ALDH1A1RAB9AMAPTMAPK1 | |
| SCHEMBL28082270 | 0.70 | NPSR1 (0.44) | NPSR1ALDH1A1RAB9AMAPTMAPK1 | |
| SCHEMBL11034554 | 0.69 | ALDH1A1 (0.48) | ALDH1A1RAB9AMAPTMAPK1NPC1 | |
| SCHEMBL11034553 | 0.69 | ALDH1A1 (0.48) | ALDH1A1RAB9AMAPTMAPK1NPC1 | |
| SCHEMBL149652 | 0.69 | NPSR1 (0.40) | NPSR1ALDH1A1RAB9AMAPTMAPK1 | |
| SCHEMBL149651 | 0.69 | NPSR1 (0.40) | NPSR1ALDH1A1RAB9AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091346-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2011-07-28 | — | — | WO | disclosed |