Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11034554 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTRAB9ANPC1MAPK1 | |
| SCHEMBL1565273 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTRAB9ANPC1MAPK1 | |
| SCHEMBL1565274 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTRAB9ANPC1MAPK1 | |
| SCHEMBL7761109 | 0.75 | NPC1 (0.45) | ALDH1A1MAPTRAB9ANPC1MAPK1 | |
| SCHEMBL29446269 | 0.75 | HPGD (0.55) | ALDH1A1MAPTMAPK1L3MBTL1KMT2A | |
| SCHEMBL27796102 | 0.75 | HPGD (0.55) | ALDH1A1MAPTMAPK1L3MBTL1KMT2A | |
| SCHEMBL12411238 | 0.75 | LMNA (0.48) | ALDH1A1MAPTL3MBTL1KMT2ALMNA | |
| SCHEMBL15494364 | 0.72 | FAAH (0.47) | ALDH1A1MAPTRAB9ANPC1MAPK1 | |
| SCHEMBL12411237 | 0.70 | KMT2A (0.47) | ALDH1A1MAPTRAB9ANPC1MAPK1 | |
| SCHEMBL9015118 | 0.70 | MCL1 (0.52) | ALDH1A1MAPTRAB9ANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59044348-A | — | — | None | — | — | JP | disclosed |
| JP-S5944348-A | ALPHA-AMINO-ALPHA-CYANO-BETA-SUBSTITUTED ENAMINE DERIVATIVE | SANPO KAGAKU KENKYUSHO:KK | 1984-03-12 | — | — | JP | disclosed |