Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12517341 | 1.00 | KDM4E (0.61) | KDM4EALDH1A1LMNAL3MBTL1NPSR1 | |
| SCHEMBL2228132 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1LMNAL3MBTL1NPSR1 | |
| Water SCHEMBL2228975 | 0.84 | KDM4E (0.54) | KDM4EALDH1A1LMNAL3MBTL1NPSR1 | |
| SCHEMBL2229399 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1LMNAL3MBTL1HPGD | |
| SCHEMBL2229106 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1LMNAL3MBTL1HPGD | |
| SCHEMBL2228498 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1LMNAL3MBTL1NPSR1 | |
| SCHEMBL2228494 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1LMNAL3MBTL1NPSR1 | |
| SCHEMBL2229253 | 0.76 | RAB9A (0.47) | KDM4EALDH1A1LMNAL3MBTL1NPSR1 | |
| SCHEMBL2227307 | 0.76 | KDM4E (0.60) | KDM4EALDH1A1LMNAL3MBTL1NPSR1 | |
| SCHEMBL2228416 | 0.76 | KDM4E (0.60) | KDM4EALDH1A1LMNAL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | claimed |