Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228498 | 1.00 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL2227907 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL12517341 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL2229106 | 0.77 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL2229399 | 0.77 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL15330791 | 0.73 | KDM4E (0.74) | KDM4EALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL18423661 | 0.70 | KDM4E (0.72) | KDM4EALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL2222445 | 0.70 | KDM4E (0.70) | KDM4EALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL15331840 | 0.70 | ALDH1A1 (1.00) | KDM4EALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL1580344 | 0.67 | KDM4E (0.77) | KDM4EALDH1A1HSD17B10CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | claimed |
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | disclosed |