Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22280124 | 0.85 | HTR6 (0.34) | HTR6HTR2AHTR2CHTR7HTR1A | |
| SCHEMBL22265876 | 0.72 | CHRM3 (0.35) | HTR6CXCR2HTR2AHTR2CSLC6A2 | |
| SCHEMBL22265836 | 0.71 | ALDH1A1 (0.38) | L3MBTL1 | |
| SCHEMBL22265851 | 0.71 | KMT2A (0.36) | HTR6CXCR2HTR2AHTR2CSLC6A2 | |
| SCHEMBL799175 | 0.67 | HTR2A (0.55) | HTR6CXCR2HTR2AHTR2CDRD2 | |
| SCHEMBL22265913 | 0.64 | MCL1 (0.32) | HTR6ATM | |
| SCHEMBL22280117 | 0.63 | KMT2A (0.36) | HTR6HTR2AHTR7HTR1ADRD2 | |
| SCHEMBL28261315 | 0.63 | CXCR2 (0.33) | CXCR2HTR2AHTR2CL3MBTL1 | |
| SCHEMBL22266033 | 0.63 | NR3C2 (0.36) | HTR6 | |
| SCHEMBL20284412 | 0.62 | HTR2A (0.49) | HTR2AHTR2CDRD2ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154321-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-07-30 | — | — | WO | disclosed |