Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20902781 | 0.91 | CA1 (0.65) | CA1CA2ANPEPERAP2MEN1 | |
| SCHEMBL338386 | 0.87 | BCHE (0.52) | LMNA | |
| SCHEMBL3969937 | 0.85 | CA1 (0.54) | CA1CA2ANPEPERAP2MEN1 | |
| SCHEMBL4396092 | 0.84 | LMNA (0.77) | LMNAMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL25381118 | 0.83 | CA1 (0.58) | CA1CA2ANPEPERAP2MEN1 | |
| SCHEMBL3959831 | 0.82 | MEN1 (0.63) | LMNACA1CA2ANPEPERAP2 | |
| SCHEMBL12952776 | 0.82 | CA1 (0.56) | LMNACA1CA2ANPEPERAP2 | |
| SCHEMBL4029852 | 0.82 | LMNA (0.62) | LMNACA1CA2ANPEPERAP2 | |
| SCHEMBL10223555 | 0.82 | CA1 (0.54) | CA1CA2ANPEPERAP2KMT2A | |
| SCHEMBL12829576 | 0.81 | CA1 (0.57) | CA1CA2ANPEPERAP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154431-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | LYNCH KEVIN R (US) | 2020-07-30 | — | — | WO | disclosed |