SCHEMBL338386

SCHEMBL338386

CCc1ccc(C(C)(C)C)cc1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BCHE P06276 12/20 0.52
ACHE P22303 12/20 0.52
TSHR P16473 2/20 0.50
LMNA P02545 1/20 0.48
TYR P14679 1/20 0.48
TP53 P04637 2/20 0.47
KCNH2 Q12809 1/20 0.47
GRIA4 P48058 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
APP P05067 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18643754 0.93 KIF11 (0.52) BCHEACHETSHRLMNATYR
SCHEMBL27879524 0.89 LMNA (0.70) TSHRLMNATYR
SCHEMBL12752952 0.89 KCNH2 (0.44) BCHEACHETSHRLMNATYR
SCHEMBL14544222 0.89 KCNH2 (0.44) BCHEACHETSHRLMNATYR
SCHEMBL13488797 0.87 BCHE (0.42) BCHEACHETSHRLMNATYR
SCHEMBL22280328 0.87 LMNA (0.59) LMNA
SCHEMBL13997210 0.87 CA1 (0.45) BCHEACHELMNAGRIA4
SCHEMBL20805343 0.87 RAB9A (0.59) BCHEACHEAPP
SCHEMBL13676635 0.87 PLAU (0.44) BCHEACHETSHRLMNATYR
SCHEMBL11849097 0.85 TSHR (0.46) BCHEACHETSHRLMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118437399-A Preparation method of molecularly imprinted polymer catalyst for synthesizing p-tert-butylethylbenzene 江苏正丹化学工业股份有限公司 2024-08-06 CN claimed
CN-117964447-A Method for preparing p-tert-butylstyrene 中国石油化工股份有限公司 2024-05-03 CN claimed
CN-117658761-A Dehydrogenation synthesis method and system of tert-butylstyrene 中国石油化工股份有限公司 2024-03-08 CN claimed
CN-115872824-A Preparation method of p-tert-butyl ethylbenzene 中国石油化工股份有限公司 2023-03-31 CN claimed
EP-2567940-A1 Method for preparing clays having novel physical-chemical properties Ecole De Biologie Industrielle (EBI) (FR) 2013-03-13 EP claimed
WO-2004110966-A1 DEHYDROGENATTION OF ALKYL AROMATIC COMPOUND OVER A GALLIUM-ZINC CATALYST DOW GLOBAL TECHNOLOGIES, INC. (US) 2004-12-23 WO claimed
US-6503662-B1 Tert-butylbenzene derivative prevents oxidation and decomposition of solvent at the time of charging which causes decreased battery characteristics UBE INDUSTRIES, LTD. (JP) 2003-01-07 US claimed
EP-0826740-B1 Symmetrical perylene dimers XEROX CORP (US) 2002-10-16 EP claimed
EP-0861878-B1 Unsymmetrical perylene dimers XEROX CORP (US) 2001-10-24 EP claimed
US-5157184-A Inorganic pyrophosphate-containing catalyst AMOCO CORPORATION (US) 1992-10-20 US claimed
EP-0192492-B1 PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1992-01-02 EP claimed
US-4843168-A HYDROGENATION CATALYST CONTAINING MAGNESIUM, ALUMINUM AMOCO CORPORATION (US) 1989-06-27 US claimed
US-4471146-A ALKALINE EARTH NICKEL PHOSPHATE CATALYST, VINYL AROMATICS THE DOW CHEMICAL COMPANY (US) 1984-09-11 US claimed
JP-60115534-A None JP disclosed
CN-121758238-A Preparation method of p-tert-butylethylbenzene 中国石油化工股份有限公司 2026-03-31 CN disclosed
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor BRILLIANT LIGHT POWER, INC. (US) 2026-02-03 US disclosed
US-4143045-A METHOD OF PREPARING DIBENZOTHIAZOLYL DISULFIDES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-03-06 US disclosed
US-4136123-A ALKALI METAL SULFONATE DERIVATIVES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-01-23 US disclosed
US-4054733-A MOLDING MATERIALS THE DOW CHEMICAL COMPANY (US) 1977-10-18 US disclosed
US-3996193-A POLYALKYLENEPOLYAMINES, DIOLEFIN RUBBER THE DOW CHEMICAL COMPANY (US) 1976-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor SCO2, SOD1, HAO2 BCHE 2326/4885ACHE 2663/4885TSHR 830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.