Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 16/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 4/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14840095 | 0.86 | KDM4E (0.52) | IMPDH2EDNRAAAK1 | |
| SCHEMBL22280594 | 0.84 | EDNRA (0.45) | IMPDH2IMPDH1EDNRAAAK1 | |
| SCHEMBL22280423 | 0.76 | FAAH (0.43) | — | |
| SCHEMBL24026537 | 0.76 | IMPDH2 (0.43) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL24026459 | 0.76 | IMPDH2 (0.44) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL7723821 | 0.76 | IMPDH2 (0.47) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL21376047 | 0.76 | IMPDH2 (0.52) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL24720275 | 0.76 | IMPDH2 (0.46) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL30930931 | 0.76 | IMPDH2 (0.46) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL20150098 | 0.74 | AAK1 (0.46) | IMPDH2IMPDH1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020153431-A1 | ESTER COMPOUND | 第一三共株式会社 | 2020-07-30 | — | — | WO | disclosed |
| WO-2020153431-A1 | ESTER COMPOUND | 第一三共株式会社 | 2020-07-30 | — | — | WO | disclosed |