Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 4/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ERG | P11308 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22265344 | 0.99 | SMO (0.46) | SMODGAT1HSD11B1GRM5LMNA | |
| Hydrochloric Acid SCHEMBL22265341 | 0.99 | SMO (0.46) | SMODGAT1HSD11B1GRM5LMNA | |
| SCHEMBL22265591 | 0.89 | HSD11B1 (0.52) | SMODGAT1HSD11B1GRM5LMNA | |
| SCHEMBL22265594 | 0.89 | HSD11B1 (0.52) | SMODGAT1HSD11B1GRM5LMNA | |
| SCHEMBL22280492 | 0.84 | SPHK2 (0.41) | SMODGAT1HSD11B1GRM5SMN1; SMN2 | |
| SCHEMBL29523928 | 0.84 | SMO (0.47) | SMODGAT1HSD11B1LMNAMAPT | |
| SCHEMBL22280489 | 0.84 | SPHK2 (0.48) | HSD11B1GRM5LMNAMAPTHTT | |
| Hydrochloric Acid SCHEMBL22265586 | 0.83 | SPHK2 (0.40) | SMODGAT1HSD11B1GRM5SPHK2 | |
| Hydrochloric Acid SCHEMBL22265583 | 0.83 | SPHK2 (0.40) | SMODGAT1HSD11B1GRM5SPHK2 | |
| SCHEMBL22280479 | 0.82 | MAPK1 (0.49) | HSD11B1GRM5LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154431-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | LYNCH KEVIN R (US) | 2020-07-30 | — | — | WO | disclosed |