Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 9/20 | 0.39 |
| ▸ | RORC | P51449 | 6/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22280768 | 0.87 | DDR1 (0.34) | DDR1RORC | |
| SCHEMBL22280577 | 0.85 | RORC (0.35) | DDR1RORC | |
| SCHEMBL18498639 | 0.85 | DDR1 (0.39) | DDR1RORCSCN9AIRAK4PTPN1 | |
| SCHEMBL18013098 | 0.84 | DDR1 (0.39) | DDR1RORCSCN9AIRAK4 | |
| SCHEMBL31534708 | 0.84 | DDR1 (0.39) | DDR1RORCSCN9AIRAK4 | |
| SCHEMBL20465987 | 0.83 | ALDH1A1 (0.33) | DDR1RORCSCN9AIRAK4PTPN1 | |
| SCHEMBL22419058 | 0.83 | RORC (0.34) | DDR1RORC | |
| SCHEMBL21998965 | 0.80 | DDR1 (0.35) | DDR1RORCSCN9APTPN1 | |
| SCHEMBL18506241 | 0.79 | POLB (0.44) | DDR1RORCSCN9A | |
| SCHEMBL31141508 | 0.79 | POLB (0.44) | DDR1RORCSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10772332-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2020-09-15 | — | — | US | disclosed |
| US-20200236940-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10772332-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | CYP4X1, CYP1A1, CYP1A2 | DDR1 2858/4885RORC 3196/4885SCN9A 1921/4885 |
| US-20200236940-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES | CYP4X1, CYP1A1, CYP1A2 | DDR1 2858/4885RORC 3196/4885SCN9A 1921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.