Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716310 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1PDK2NPC1LMNA | |
| SCHEMBL30005971 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1PDK2NPC1LMNA | |
| SCHEMBL1435465 | 0.76 | PTPN1 (0.61) | HNF4AKDM4EALDH1A1HSD17B10ALB | |
| SCHEMBL5678745 | 0.75 | HNF4A (0.76) | HNF4AKDM4EALDH1A1HSD17B10ALB | |
| SCHEMBL15741721 | 0.74 | PARP1 (0.49) | KDM4EALDH1A1HSD17B10HPGDPDK2 | |
| SCHEMBL10948911 | 0.73 | HNF4A (0.73) | HNF4AKDM4EALDH1A1HSD17B10ALB | |
| SCHEMBL19283566 | 0.72 | IMPDH2 (0.43) | KDM4EALDH1A1PDK2NPC1LMNA | |
| SCHEMBL26259988 | 0.72 | MEN1 (0.48) | PDK2LMNAPKMIMPDH2IMPDH1 | |
| SCHEMBL25568050 | 0.71 | HNF4A (0.54) | HNF4AKDM4EALDH1A1HSD17B10ALB | |
| SCHEMBL14840095 | 0.71 | KDM4E (0.52) | KDM4EALDH1A1LMNAIMPDH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020153431-A1 | ESTER COMPOUND | 第一三共株式会社 | 2020-07-30 | — | — | WO | disclosed |
| WO-2020153431-A1 | ESTER COMPOUND | 第一三共株式会社 | 2020-07-30 | — | — | WO | disclosed |