Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915895 | 0.77 | SIGMAR1 (0.44) | PARP1LMNAGAAL3MBTL1MAPT | |
| SCHEMBL21818680 | 0.76 | PARP1 (0.40) | PARP1GFERSMN1; SMN2 | |
| SCHEMBL773340 | 0.72 | CD44 (0.54) | PARP1LMNAGAAL3MBTL1 | |
| SCHEMBL773339 | 0.72 | CD44 (0.54) | PARP1LMNAGAAL3MBTL1 | |
| SCHEMBL1597761 | 0.71 | BCL2L1 (0.53) | — | |
| SCHEMBL26130065 | 0.71 | CD44 (0.47) | PARP1LMNAGAAMAPT | |
| SCHEMBL30817469 | 0.71 | BCL2L1 (0.53) | — | |
| SCHEMBL19835774 | 0.67 | ADRA2A (0.47) | — | |
| SCHEMBL10615520 | 0.67 | PARP1 (0.37) | PARP1SMN1; SMN2 | |
| SCHEMBL9120020 | 0.67 | AKR1C3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020153431-A1 | ESTER COMPOUND | 第一三共株式会社 | 2020-07-30 | — | — | WO | disclosed |