SCHEMBL2228073

SCHEMBL2228073

N[C@@H](C=O)[C@H](O)[C@@H](O)[C@H](O)CO

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TDP1 Q9NUW8 1/20 0.50
USP2 O75604 1/20 0.50
SLCO1B1 Q9Y6L6 1/20 0.50
PAX8 Q06710 1/20 0.46
PDE4A P27815 1/20 0.43
AKR1B1 P15121 1/20 0.40
KDM4E B2RXH2 2/20 0.38
TOP1 P11387 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706423 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL8586304 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL420278 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL17493340 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL2066243 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL1548302 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL2227363 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL3116850 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL22963142 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL28730 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2149581-A1 MONOMER AND COMPOSITION FOR PRODUCING LOW-PERCENTAGE HYDROGEL AND/OR HYDROGEL HAVING A LOW CROSS LINKAGE CONTENT, A HYDROGEL AND A BIOCHIP BASED THEREON Institut Molekulyarnoi Biologii Im. V.A. Engelgardta Rossiiskoi Akademii Nauk (RU) 2010-02-03 EP claimed
US-20040029815-A1 Compositions and methods for treating cancer THRESHOLD PHARMACEUTICALS, INC. 2004-02-12 US claimed
WO-2003082301-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER THRESHOLD PHARMACEUTICALS, INC. (US) 2003-10-09 WO claimed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
CN-113906144-A Optimal chromosomal insertion loci 因比奥斯公司 2022-01-07 CN disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed
US-9045514-B2 Methods for producing amino-substituted glycolipid compounds DUPONT NUTRITION BIOSCIENCES APS (DK) 2015-06-02 US disclosed
EP-0829104-A1 HIGH ENERGY DENSITY VANADIUM ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND ALL-VANADIUM REDOX CELLS AND BATTERIES CONTAINING HIGH ENERGY VANADIUM ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1998-03-18 EP disclosed
US-5631389-A SUCCINAMIDES WITH SUGAR GROUPS, POLLUTION CONTROL, BIODEGRADABLE LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-05-20 US disclosed
EP-0729648-A4 STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS UNISEARCH LTD (AU) 1997-01-02 EP disclosed
WO-1996035239-A1 HIGH ENERGY DENSITY VANADIUM ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND ALL-VANADIUM REDOX CELLS AND BATTERIES CONTAINING HIGH ENERGY VANADIUM ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1996-11-07 WO disclosed
EP-0729648-A1 STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1996-09-04 EP disclosed
US-5541341-A CARBOHYDRATE BASED SURFACTANTS LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1996-07-30 US disclosed
WO-1995012219-A1 STABILISED ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND REDOX CELLS AND BATTERIES CONTAINING STABILISED ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1995-05-04 WO disclosed
EP-0059911-A1 Cis-platinous(II) complexes with saccharide derivatives as ligands BASF Aktiengesellschaft (DE) 1982-09-15 EP disclosed
US-4224440-A NON-IONIC X-RAY CONTRAST AGENTS MALLINCKRODT, INC. (US) 1980-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040029815-A1 Compositions and methods for treating cancer SLC2A2, SLC2A1, SLC2A3 LMNA 1299/4885L3MBTL1 2810/4885TDP1 2319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.