SCHEMBL2066243

SCHEMBL2066243

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nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TDP1 Q9NUW8 1/20 0.50
USP2 O75604 1/20 0.50
SLCO1B1 Q9Y6L6 1/20 0.50
PAX8 Q06710 1/20 0.46
PDE4A P27815 1/20 0.43
AKR1B1 P15121 1/20 0.40
KDM4E B2RXH2 2/20 0.38
TOP1 P11387 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706423 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL8586304 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL420278 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL17493340 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL2228073 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL1548302 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL2227363 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL3116850 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL22963142 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL28730 1.00 LMNA (0.52) LMNAL3MBTL1TDP1USP2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0320960-B1 AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1993-05-12 EP claimed
US-5145848-A AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1992-09-08 US claimed
EP-0396588-A1 AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1990-11-14 EP claimed
WO-1989005815-A1 AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1989-06-29 WO claimed
EP-0320960-A1 Amino anthracenediones-bis platinum complexes, useful as antitumoral agents BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1989-06-21 EP claimed
WO-2024058984-A2 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES MarvelBiome, Inc. (US) 2024-03-21 WO disclosed
WO-2015091643-A1 BIOLOGICAL CULTURE OF A STRAIN OF THE SPECIES PSEUDOMONAS GRAMINIS AND USE OF SAID CULTURE AS ANTAGONIST FOR THE BIOCONTROL OF PATHOGENIC BACTERIA UNIVERSITAT DE LLEIDA (ES) 2015-06-25 WO disclosed
US-8148321-B2 Bioconjugates as therapeutic agent and synthesis thereof NATIONAL INSTITUTE OF IMMUNOLOGY (US) 2012-04-03 US disclosed
US-20090088372-A1 Novel Bioconjugates As Therapeutic Agent and Synthesis Thereof NATIONAL INSTITUTE OF IMMUNOLOGY (IN) 2009-04-02 US disclosed
EP-1996236-A2 NOVEL BIOCONJUGATES AS THERAPEUTIC AGENT AND SYNTHESIS THEREOF National Institute of Immunology (IN) 2008-12-03 EP disclosed
EP-1876914-A2 LIGNAN-CONTAINING COMPOSITIONS Archer-Daniels-Midland Company (US) 2008-01-16 EP disclosed
WO-2007108013-A2 NOVEL BIOCONJUGATES AS THERAPEUTIC AGENT AND SYNTHESIS THEREOF NATIONAL INSTITUTE OF IMMUNOLOGY (IN) 2007-09-27 WO disclosed
WO-2005079764-A1 COMPOSITIONS AND METHODS FOR TIMED RELEASE OF WATER-SOLUBLE NUTRITIONAL SUPPLEMENTS OSMOPHARM USA (US) 2005-09-01 WO disclosed
WO-2005056525-A2 DEACETYLATION OF N-ACETYLGLUCOSAMINE BIO-TECHNICAL RESOURCES (US) 2005-06-23 WO disclosed
US-6242583-B1 COUPLING CARBOHYDRATE COMPOUNDS IN PRESENCE OF PROMOTER TO A FUNCTIONALIZED SOLID SUPPORT BASF AKTIENGESELLSCHAFT (DE) 2001-06-05 US disclosed
US-5622693-A WATER SOLUBLE, FREEZE DRIED, SOLID MIXTURE OF POLYOXYETHYLENE GLYCOL AND A THICKENER OR HUMECTANT; HEAT RESISTANCE, SKIN FEEL SHISEIDO COMPANY LTD. (JP) 1997-04-22 US disclosed
EP-0320960-B1 AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1993-05-12 EP disclosed
US-5145848-A AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1992-09-08 US disclosed
EP-0412449-A2 Solid cosmetic composition SHISEIDO COMPANY LIMITED (JP) 1991-02-13 EP disclosed
EP-0320960-A1 Amino anthracenediones-bis platinum complexes, useful as antitumoral agents BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1989-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090088372-A1 Novel Bioconjugates As Therapeutic Agent and Synthesis Thereof DNPEP, LNPEP, RNPEP LMNA 1551/4885L3MBTL1 1253/4885TDP1 1325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.