SCHEMBL22280911

SCHEMBL22280911

Cc1cc(C)c(-c2ccc3c(c2)c2ccc(O)cc2c2nccn32)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CCNE1 P24864 3/20 0.33
CDK2 P24941 3/20 0.33
CCNE2 O96020 1/20 0.33
TLR8 Q9NR97 1/20 0.33
GRIA1 P42261 1/20 0.33
IKBKB O14920 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22262082 0.93 CDK2 (0.33) CCNE1CDK2CCNE2TLR8GRIA1
SCHEMBL22281206 0.85 DRD1 (0.33) IKBKBKDM4EALDH1A1LMNAHPGD
SCHEMBL22280909 0.84 BCHE (0.39) TLR8KDM4EALDH1A1LMNAHPGD
SCHEMBL22262081 0.81 ESR1 (0.39) CCNE1CDK2CCNE2ESR1ESR2
SCHEMBL20561490 0.81 IKBKB (0.35) CCNE1CDK2CCNE2TLR8GRIA1
SCHEMBL22280910 0.80 KDM4E (0.34) KDM4EALDH1A1LMNAHPGD
SCHEMBL22280898 0.79 GRIA1 (0.31) CCNE1CDK2GRIA1IKBKB
SCHEMBL22281107 0.78 DRD1 (0.33) IKBKBKDM4EALDH1A1LMNAHPGD
SCHEMBL22280693 0.78 RORA (0.35) CCNE1CDK2CCNE2IKBKBALDH1A1
SCHEMBL22349169 0.76 CCNE1 (0.37) CCNE1CDK2CCNE2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200239505-A1 BLUE PHOSPHORESCENT EMITTERS EMPLOYING FUNCTIONALIZED IMIDAZOPHENTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2020-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200239505-A1 BLUE PHOSPHORESCENT EMITTERS EMPLOYING FUNCTIONALIZED IMIDAZOPHENTHRIDINE AND ANALOGUES EML4, TYR, TYMP CCNE1 3005/4885CDK2 435/4885CCNE2 1501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.