SCHEMBL22281101

SCHEMBL22281101

CC(C)(C)c1ccc2c(c1)c1ccc(Oc3ccc4c(c3)c3nccn3c3cccnc43)cc1c1nccn21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.34
P2RY1 P47900 2/20 0.32
BRAF P15056 5/20 0.31
RAF1 P04049 1/20 0.31
FGFR2 P21802 1/20 0.31
PGR P06401 1/20 0.31
RORA P35398 1/20 0.31
RORC P51449 1/20 0.31
RORB Q92753 1/20 0.31
KDR P35968 2/20 0.30
CYP3A4 P08684 2/20 0.30
TNK2 Q07912 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30
PDGFRB P09619 1/20 0.30
KIT P10721 1/20 0.30
SRC P12931 1/20 0.30
FLT1 P17948 1/20 0.30
FLT4 P35916 1/20 0.30
TACR1 P25103 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22280928 0.90 PPARG (0.36) PPARGP2RY1BRAFRAF1FGFR2
SCHEMBL22280692 0.90 FGFR2 (0.36) BRAFRAF1FGFR2PGRRORA
SCHEMBL22281105 0.89 PGR (0.37) PPARGBRAFRAF1FGFR2PGR
SCHEMBL22281208 0.85 MAPT (0.34) PPARGFGFR2PGRRORARORC
SCHEMBL22280941 0.83 TNK2 (0.35) TNK2TACR1
SCHEMBL22280926 0.83 FGFR2 (0.36) PPARGBRAFRAF1FGFR2KDR
SCHEMBL22281106 0.82 CASR (0.40) FGFR2PGRRORARORCRORB
SCHEMBL22280917 0.82 PDE4A (0.32)
SCHEMBL21917512 0.80 MEN1 (0.43)
SCHEMBL22280716 0.77 MAPT (0.36) TNK2TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200239505-A1 BLUE PHOSPHORESCENT EMITTERS EMPLOYING FUNCTIONALIZED IMIDAZOPHENTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2020-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200239505-A1 BLUE PHOSPHORESCENT EMITTERS EMPLOYING FUNCTIONALIZED IMIDAZOPHENTHRIDINE AND ANALOGUES EML4, TYR, TYMP PPARG 1844/4885P2RY1 123/4885BRAF 953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.