SCHEMBL2228151

SCHEMBL2228151

CCC(C)(C)c1cc(C)cc(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
MAPT P10636 2/20 0.41
CNR2 P34972 9/20 0.40
CNR1 P21554 5/20 0.40
SMN1; SMN2 Q16637 4/20 0.38
MAPK1 P28482 2/20 0.38
LMNA P02545 1/20 0.38
CASP3 P42574 1/20 0.38
ATM Q13315 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
ALDH1A1 P00352 3/20 0.35
TSHR P16473 1/20 0.35
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
HSPA5 P11021 1/20 0.34
MEN1 O00255 1/20 0.33
GLA P06280 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4363284 0.95 SMN1; SMN2 (0.38) NPC1RAB9AMAPTCNR2CNR1
SCHEMBL19354870 0.84 NPC1 (0.33) NPC1RAB9AMAPTCNR2CNR1
SCHEMBL12482514 0.84 CNR2 (0.35) NPC1RAB9AMAPTCNR2CNR1
SCHEMBL15978710 0.84 RAPGEF4 (0.43) NPC1RAB9AMAPTCNR2CNR1
SCHEMBL780091 0.83 NPC1 (0.43) NPC1RAB9AMAPTCNR2SMN1; SMN2
Phenol SCHEMBL28107433 0.82 ESR1 (0.41) NPC1RAB9ACNR2CNR1SMN1; SMN2
SCHEMBL10342305 0.78 NPC1 (0.41) NPC1RAB9AMAPTCNR2CNR1
SCHEMBL24653295 0.77 NPC1 (0.48) NPC1RAB9AMAPTSMN1; SMN2MAPK1
SCHEMBL21557594 0.77 NPC1 (0.48) NPC1RAB9AMAPTSMN1; SMN2MAPK1
SCHEMBL9212289 0.77 CNR2 (0.35) CNR2CNR1SMN1; SMN2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080254367-A1 Anode composite of lithium oxide with cobalt oxide or nickel oxide; cathode is lithium, or alloy thereof; nonaqueous electrolyte; prevention decomposition due to overcharging UBE INDUSTRIES, LTD. (JP) 2008-10-16 US claimed
US-20130330607-A1 ELECTROLYTIC SOLUTION AND LITHIUM-ION SECONDARY BATTERY KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2013-12-12 US disclosed
US-8394541-B2 Lithium secondary battery and non-aqueous electrolytic solution UBE INDUSTRIES, LTD. (JP) 2013-03-12 US disclosed
US-20110250504-A1 LITHIUM SECONDARY BATTERY AND NON-AQUEOUS ELECTROLYTIC SOLUTION UBE INDUSTRIES, LTD. (JP) 2011-10-13 US disclosed
US-7981552-B2 Lithium secondary battery and non-aqueous electrolytic solution UBE INDUSTRIES, LTD. (JP) 2011-07-19 US disclosed
US-7615316-B2 Nonaqueous electrolytic solution and lithium secondary batteries UBE INDUSTRIES, LTD. (JP) 2009-11-10 US disclosed
US-20080254367-A1 Anode composite of lithium oxide with cobalt oxide or nickel oxide; cathode is lithium, or alloy thereof; nonaqueous electrolyte; prevention decomposition due to overcharging UBE INDUSTRIES, LTD. (JP) 2008-10-16 US disclosed
EP-1361622-B1 NONAQUEOUS ELECTROLYTIC SOLUTION AND LITHIUM SECONDARY BATTERIES UBE INDUSTRIES (JP) 2008-06-04 EP disclosed
US-20080050658-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND LITHIUM SECONDARY BATTERIES UBE INDUSTRIES, LTD. (JP) 2008-02-28 US disclosed
US-7294436-B2 Nonaqueous electrolytic solution and lithium secondary batteries UBE INDUSTRIES, LTD. (JP) 2007-11-13 US disclosed
US-20040028996-A1 Lithium secondary cell and nonaqueous electrolyte UBE INDUSTRIES, LTD. (JP) 2004-02-12 US disclosed
EP-1361622-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND LITHIUM SECONDARY BATTERIES Ube Industries, Ltd. (JP) 2003-11-12 EP disclosed
EP-1324417-A1 LITHIUM SECONDARY CELL AND NONAQUEOUS ELECTROLYTE Ube Industries, Ltd. (JP) 2003-07-02 EP disclosed
EP-0575852-B1 Process for preparing dinitro-polyalkyl-benzenes BAYER AG (DE) 1996-10-09 EP disclosed
US-5367108-A Process for the preparation of dinitro-polyalkylbenzenes BAYER AKTIENGESELLSCHAFT (DE) 1994-11-22 US disclosed
EP-0575852-A1 Process for preparing dinitro-polyalkyl-benzenes BAYER AG (DE) 1993-12-29 EP disclosed
EP-0125591-B1 TRIALKYL-SUBSTITUTED AROMATIC DIISOCYANATES BASF Aktiengesellschaft (DE) 1987-05-06 EP disclosed
EP-0069286-B1 PROCESS FOR THE PRODUCTION OF POSSIBLY CELLULAR POLYURETHANE POLYUREA MOULDED ARTICLES, AND ALKYL- SUBSTITUTED PHENYLENE DIAMINES FOR THAT PURPOSE BASF Aktiengesellschaft (DE) 1985-09-18 EP disclosed
EP-0125591-A1 Trialkyl-substituted aromatic diisocyanates BASF Aktiengesellschaft (DE) 1984-11-21 EP disclosed
EP-0069286-A1 Process for the production of possibly cellular polyurethane polyurea moulded articles, and alkyl- substituted phenylene diamines for that purpose BASF Aktiengesellschaft (DE) 1983-01-12 EP disclosed