SCHEMBL2228160

SCHEMBL2228160

c1cn(-c2nccs2)cn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.41
CYP1A2 P05177 2/20 0.40
CYP1A1 P04798 1/20 0.40
CYP1B1 Q16678 1/20 0.40
LMNA P02545 4/20 0.39
GLA P06280 1/20 0.39
MAPT P10636 1/20 0.38
ENPP2 Q13822 1/20 0.38
MKNK1 Q9BUB5 1/20 0.38
MKNK2 Q9HBH9 1/20 0.38
NOTUM Q6P988 1/20 0.38
CYP2A6 P11509 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
TSHR P16473 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
IDO1 P14902 2/20 0.36
ALOX15 P16050 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.35
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27807426 0.89 LMNA (0.36) CYP3A4CYP1A2CYP1A1CYP1B1LMNA
SCHEMBL1245039 0.76 LMNA (0.46) LMNAGLAMAPTTDP1TSHR
SCHEMBL8721409 0.68 IDO1 (0.46) CYP3A4CYP1A2CYP1A1CYP1B1LMNA
SCHEMBL9220581 0.68 CYP3A4 (0.38) CYP3A4CYP1A2LMNAMAPTENPP2
SCHEMBL2628931 0.68 CYP3A4 (0.39) CYP3A4CYP1A2LMNAMAPTENPP2
SCHEMBL244552 0.68 CYP3A4 (0.38) CYP3A4CYP1A2LMNAMAPTENPP2
SCHEMBL9925916 0.67 L3MBTL1 (0.39) CYP3A4CYP1A2LMNAGLAMAPT
SCHEMBL18708315 0.67 LMNA (0.43) CYP3A4CYP1A2CYP1A1CYP1B1LMNA
SCHEMBL12402348 0.67 CYP3A4 (0.37) CYP3A4CYP1A2CYP1A1CYP1B1LMNA
SCHEMBL18708314 0.67 CHEK1 (0.39) CYP3A4CYP1A2CYP1A1CYP1B1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117568743-B Surface corrosion-resistant wear-resistant treatment process for iron-based material 江苏普坦科金属科技有限公司 2024-03-19 CN claimed
CN-117568743-A Surface corrosion-resistant wear-resistant treatment process for iron-based material 江苏普坦科金属科技有限公司 2024-02-20 CN claimed
CN-101479259-A Urea derivatives of piperidine or pyrrolidine, their preparation and therapeutic use SANOFI AVENTIS (FR) 2009-07-08 CN claimed
CN-120035427-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-05-23 CN disclosed
CN-119968189-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-05-09 CN disclosed
CN-119894486-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-04-25 CN disclosed
CN-119855579-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-04-18 CN disclosed
CN-119836282-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-04-15 CN disclosed
CN-118785891-A Composition for lightening keratin fibers and method for lightening keratin fibers using the same 莱雅公司 2024-10-15 CN disclosed
CN-118785890-A Method for lightening keratin fibres or for simultaneously bleaching and dyeing keratin fibres 莱雅公司 2024-10-15 CN disclosed
CN-118714994-A Composition for lightening keratin fibers and method for lightening keratin fibers using the same 莱雅公司 2024-09-27 CN disclosed
EP-1711180-A1 THIAZOLYLIMIDAZOLE DERIVATIVES AND THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN MERCK PATENT GmbH (DE) 2006-10-18 EP disclosed
EP-1711180-A1 THIAZOLYLIMIDAZOLE DERIVATIVES AND THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN MERCK PATENT GmbH (DE) 2006-10-18 EP disclosed
CN-1835729-A Tinctorial composition comprising at least one direct dye with mixed chromophores OREAL (FR) 2006-09-20 CN disclosed
CN-1835730-A Coloring lightening compositions comprising at least one direct cationic dye with mixed chromophores OREAL (FR) 2006-09-20 CN disclosed
WO-2005085241-A1 THIAZOLE DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2005-09-15 WO disclosed
WO-2005074934-A1 THIAZOLYLIMIDAZOLE DERIVATIVES AND THEIR USE AS INHIBITORS OF MICROSMAL TRIGLYCE RIDE TRANSFER PROTEIN MERCK PATENT GMBH (DE) 2005-08-18 WO disclosed
WO-2005074934-A1 THIAZOLYLIMIDAZOLE DERIVATIVES AND THEIR USE AS INHIBITORS OF MICROSMAL TRIGLYCE RIDE TRANSFER PROTEIN MERCK PATENT GMBH (DE) 2005-08-18 WO disclosed
EP-1432691-A1 IMIDAZOLE-4-CARBOXAMIDE DERIVATIVES, PREPARATION AND USE THEREOF FOR TREATMENT OF OBESITY Bayer Pharmaceuticals Corporation (US) 2004-06-30 EP disclosed
WO-2003040107-A1 IMIDAZOLE-4-CARBOXAMIDE DERIVATIVES, PREPARATION AND USE THEREOF FOR TREATMENT OF OBESITY BAYER PHARMACEUTICALS CORPORATION (US) 2003-05-15 WO disclosed