Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8225536 | 0.79 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTHPGDRAB9A | |
| SCHEMBL26033043 | 0.72 | TAAR1 (0.40) | ALDH1A1MAPTHPGDKDM4EGAA | |
| SCHEMBL22427662 | 0.71 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTHPGDRAB9A | |
| SCHEMBL14448605 | 0.71 | ALDH1A1 (0.34) | ALDH1A1LMNAMAPTHPGDRAB9A | |
| SCHEMBL28088963 | 0.68 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTHPGDRAB9A | |
| SCHEMBL12394773 | 0.68 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTHPGDRAB9A | |
| SCHEMBL19602925 | 0.68 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTHPGDRAB9A | |
| SCHEMBL25738876 | 0.68 | ESR1 (0.33) | ALDH1A1LMNAMAPTHPGDRAB9A | |
| SCHEMBL20665639 | 0.66 | CA2 (0.40) | ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL23870329 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154447-A1 | MTORC MODULATORS AND USES THEREOF | AEOVIAN PHARMACEUTICALS, INC. (US) | 2020-07-30 | — | — | WO | disclosed |