SCHEMBL22282149

SCHEMBL22282149

CC(=O)c1cc(-c2cccc3cccnc23)cc(-c2cccc3cccnc23)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
BRD4 O60885 1/20 0.48
ALDH1A1 P00352 1/20 0.46
SERPINE1 P05121 1/20 0.46
MMP9 P14780 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
MMP2 P08253 2/20 0.44
TSHR P16473 2/20 0.44
KDM4E B2RXH2 1/20 0.44
GMNN O75496 1/20 0.44
LMNA P02545 1/20 0.44
TP53 P04637 1/20 0.44
HSP90AA1 P07900 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
MAPT P10636 1/20 0.44
ALOX15 P16050 1/20 0.44
NFKB1 P19838 1/20 0.44
MMP8 P22894 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12641874 0.86 MMP9 (0.49) MEN1KMT2AALDH1A1MMP9TDP1
SCHEMBL17334526 0.83 CCR1 (0.62) MEN1KMT2ABRD4MMP9TDP1
SCHEMBL18943942 0.82 CCR1 (0.46) MEN1KMT2AALDH1A1MMP9TDP1
SCHEMBL420673 0.79 PDE4A (0.54) BRD4SERPINE1LMNAPDE4APDE4B
SCHEMBL18943979 0.78 MEN1 (0.51) MEN1KMT2AALDH1A1MMP9TDP1
SCHEMBL28267408 0.78 PDE4A (0.62) MEN1KMT2ABRD4SERPINE1TDP1
SCHEMBL418337 0.77 SLC40A1 (0.57) BRD4ALDH1A1SERPINE1LMNAALOX15
SCHEMBL18325266 0.77 BRD4 (0.46) BRD4ALDH1A1MMP9TDP1MMP2
SCHEMBL30563009 0.76 CCR1 (0.52) MEN1KMT2ABRD4ALDH1A1SERPINE1
SCHEMBL27191397 0.76 CCR1 (0.52) MEN1KMT2ABRD4ALDH1A1SERPINE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220173329-A1 COMPOUND, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE LT MATERIALS CO., LTD. (KR) 2022-06-02 US disclosed
WO-2020153740-A1 COMPOSITION, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE 엘티소재주식회사 2020-07-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220173329-A1 COMPOUND, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE OXER1, OCIAD1, OR10J3 MEN1 3525/4885KMT2A 3400/4885BRD4 3367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.