Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228281 | 0.86 | HTT (0.50) | HTTCHKAGGPS1GAALMNA | |
| SCHEMBL2229292 | 0.83 | HTT (0.61) | HTTGGPS1LMNATSHRMEN1 | |
| SCHEMBL62492 | 0.82 | — | — | |
| SCHEMBL2229224 | 0.82 | HTT (0.70) | HTTLMNATSHRMEN1KMT2A | |
| SCHEMBL2230433 | 0.80 | HTT (0.73) | HTTLMNATSHRMEN1KMT2A | |
| SCHEMBL2228939 | 0.80 | HTT (0.73) | HTTLMNATSHRMEN1KMT2A | |
| SCHEMBL2229289 | 0.80 | HTT (0.73) | HTTLMNATSHRMEN1KMT2A | |
| SCHEMBL2229002 | 0.80 | HTT (0.73) | HTTLMNATSHRMEN1KMT2A | |
| SCHEMBL2230238 | 0.80 | HTT (0.73) | HTTLMNATSHRMEN1KMT2A | |
| Bromide SCHEMBL1502745 | 0.80 | HTT (0.54) | HTTCHKATERTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730157-B1 | IONIC LIQUIDS COMPRISING FLUORALKYLTRIFFLUOROBORATE ANIONS | MERCK PATENT GMBH (DE) | 2011-07-27 | — | — | EP | disclosed |
| EP-1730157-A1 | IONIC LIQUIDS COMPRISING FLUORALKYLTRIFFLUOROBORATE ANIONS | MERCK PATENT GmbH (DE) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005105815-A1 | IONIC LIQUIDS COMPRISING FLUORALKYLTRIFFLUOROBORATE ANIONS | MERCK PATENT GMBH (DE) | 2005-11-10 | — | — | WO | disclosed |