Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | GPR183 | P32249 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19564561 | 0.91 | ALOX5 (0.57) | NPC1RAB9AGPR183ALDH1A1MAPT | |
| SCHEMBL3115263 | 0.89 | NPC1 (0.77) | NPC1RAB9AALDH1A1MAPTKMT2A | |
| SCHEMBL3122021 | 0.89 | NPC1 (0.77) | NPC1RAB9AALDH1A1MAPTKMT2A | |
| SCHEMBL3115258 | 0.89 | NPC1 (0.77) | NPC1RAB9AALDH1A1MAPTKMT2A | |
| SCHEMBL3122017 | 0.89 | NPC1 (0.77) | NPC1RAB9AALDH1A1MAPTKMT2A | |
| SCHEMBL11483173 | 0.88 | NPC1 (0.60) | NPC1RAB9AGPR183ALDH1A1MAPT | |
| SCHEMBL11483179 | 0.88 | NPC1 (0.60) | NPC1RAB9AGPR183ALDH1A1MAPT | |
| SCHEMBL20855374 | 0.86 | GPR183 (0.59) | NPC1RAB9AGPR183ALDH1A1MAPT | |
| SCHEMBL20866527 | 0.86 | RAB9A (0.81) | NPC1RAB9AGPR183ALDH1A1MAPT | |
| SCHEMBL3123638 | 0.84 | GPR183 (0.72) | NPC1RAB9AGPR183ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687311-A1 | AMIDES FOR GENERATING A TRIGEMINAL EFFECT | Symrise AG (DE) | 2020-08-05 | — | — | EP | claimed |
| EP-3687311-A1 | AMIDES FOR GENERATING A TRIGEMINAL EFFECT | Symrise AG (DE) | 2020-08-05 | — | — | EP | disclosed |