Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30244634 | 0.82 | KDM4E (0.37) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL29174208 | 0.80 | CCNC (0.47) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL22284555 | 0.79 | PTGS1 (0.49) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL4836542 | 0.77 | CCNC (0.46) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL4836538 | 0.77 | CCNC (0.46) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL1356813 | 0.77 | KDM4E (0.68) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL1124345 | 0.77 | KDM4E (0.68) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL1044002 | 0.76 | CYP11B2 (0.41) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL22284700 | 0.76 | CYP11B2 (0.36) | RAB9AKDM4ENPC1SMN1; SMN2HPGD | |
| SCHEMBL22298845 | 0.74 | FBP1 (0.41) | SMN1; SMN2HPGDALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11680057-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-20 | — | — | US | claimed |
| US-11059806-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2021-07-13 | — | — | US | disclosed |
| US-20200245625-A1 | PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11680057-B2 | Pyrazole derivatives | RB1, NQO2, RBX1 | RAB9A 949/4885KDM4E 858/4885NPC1 3943/4885 |
| US-20200245625-A1 | PYRAZOLE DERIVATIVES | RB1, NQO2, RBX1 | RAB9A 949/4885KDM4E 858/4885NPC1 3943/4885 |
| US-11059806-B2 | Pyrazole derivatives | RB1, NQO2, RBX1 | RAB9A 949/4885KDM4E 858/4885NPC1 3943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.