SCHEMBL2228487

SCHEMBL2228487

C[C@@]1(n2cnc3c(O)ncnc32)O[C@H](CO)[C@@H](O)[C@H]1S

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 2/20 0.39
PI4K2B Q8TCG2 2/20 0.39
PI4K2A Q9BTU6 2/20 0.39
PI4KB Q9UBF8 2/20 0.39
EGFR P00533 1/20 0.39
ERBB2 P04626 1/20 0.39
ADORA2A P29274 3/20 0.38
ADORA3 P0DMS8 4/20 0.36
SLC29A1 Q99808 2/20 0.36
DPP4 P27487 1/20 0.36
MEN1 O00255 1/20 0.36
SLC28A1 O00337 1/20 0.36
MAP3K7 O43318 1/20 0.36
SLC28A2 O43868 1/20 0.36
GAPDH P04406 1/20 0.36
MAPK1 P28482 1/20 0.36
ADORA2B P29275 1/20 0.36
ADORA1 P30542 1/20 0.36
STAT6 P42226 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL41364 0.90 PI4KA (0.43) PI4KAPI4K2BPI4K2API4KBADORA2A
Nitrobenzene SCHEMBL28322736 0.88 SLC29A1 (0.41) SLC29A1SLC28A3
SCHEMBL160359 0.88 EGFR (0.53) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL30515021 0.88 EGFR (0.53) PI4KAPI4K2BPI4K2API4KBEGFR
Phosphoric Acid SCHEMBL635802 0.84 PI4KA (0.40) PI4KAPI4K2BPI4K2API4KBADORA2A
Phosphoric Acid SCHEMBL28300969 0.83 EGFR (0.48) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL27541459 0.79 PI4KA (0.39) PI4KAPI4K2BPI4K2API4KBEGFR
SCHEMBL29974446 0.78 PI4KA (0.40) PI4KAPI4K2BPI4K2API4KBADORA2A
SCHEMBL14586077 0.78 PI4KA (0.41) PI4KAPI4K2BPI4K2API4KBADORA2A
SCHEMBL10365538 0.78 SLC29A1 (0.39) PI4KAPI4K2BPI4K2API4KBEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
US-20250275946-A1 COMBINATION THERAPY FOR THE TREATMENT OF CANCER UNM RAINFOREST INNOVATIONS (US) 2025-09-04 US claimed
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2024-05-02 US claimed
WO-2022169634-A9 COMBINATION THERAPY FOR THE TREATMENT OF CANCER UNM RAINFOREST INNOVATIONS (US) 2022-09-22 WO claimed
EP-4045504-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS Ai-biopharma (FR) 2022-08-24 EP claimed
WO-2022169634-A1 COMBINATION THERAPY FOR THE TREATMENT OF CANCER UNM RAINFOREST INNOVATIONS (US) 2022-08-11 WO claimed
WO-2021074443-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2021-04-22 WO claimed
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US disclosed
US-12539332-B2 Anti-viral and hepatic-targeted drugs A-BIOPHARMA (FR) 2026-02-03 US disclosed
US-20250275946-A1 COMBINATION THERAPY FOR THE TREATMENT OF CANCER UNM RAINFOREST INNOVATIONS (US) 2025-09-04 US disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO disclosed
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2024-05-02 US disclosed
WO-2022169634-A9 COMBINATION THERAPY FOR THE TREATMENT OF CANCER UNM RAINFOREST INNOVATIONS (US) 2022-09-22 WO disclosed
WO-2006135602-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS UNIVERSITY OF ROCHESTER (US) 2006-12-21 WO disclosed
US-20050119284-A1 ANTIVIRAL AGENTS AND METHODS OF USE -, Wisconsin Alumni Research Foundation (US) 2005-06-02 US disclosed
EP-1349555-A1 TREATMENT OF CANCER BY REDUCTION OF INTRACELLULAR ENERGY AND PYRIMIDINES Sloan-Kettering Institute For Cancer Research (US) 2003-10-08 EP disclosed
US-20030139331-A1 Treatment of cancer by reduction of intracellular energy and pyrimidines SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH 2003-07-24 US disclosed
EP-1239280-A2 ElogDoct:A tool for lipophilicity determination in drug discovery basic and neutral compounds Pfizer Products Inc. (US) 2002-09-11 EP disclosed
WO-2002045720-A1 TREATMENT OF CANCER BY REDUCTION OF INTRACELLULAR ENERGY AND PYRIMIDINES SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2002-06-13 WO disclosed
EP-1126277-A2 Determination of log P coefficients via A RP-HPLC column Pfizer Products Inc. (US) 2001-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539332-B2 Anti-viral and hepatic-targeted drugs HAVCR2, NR1H4, NR1H3 PI4KA 3407/4885PI4K2B 3778/4885PI4K2A 4002/4885
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS HAVCR2, NR1H4, NR1H3 PI4KA 3176/4885PI4K2B 3413/4885PI4K2A 3685/4885
US-20050119284-A1 ANTIVIRAL AGENTS AND METHODS OF USE APRT, SAMHD1, GART PI4KA 2425/4885PI4K2B 2853/4885PI4K2A 3089/4885
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS SLC10A1, HAVCR2, HDGF PI4KA 1840/4885PI4K2B 2425/4885PI4K2A 3004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.