Sugi Predict

Sugi Predict / Compounds / SCHEMBL22285129

SCHEMBL22285129

SCHEMBL22285129

CC(C)(C)OC(=O)NC(C(=O)O)C1CCCCCC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CTSS P25774 2/20 0.47
▸ CTSK P43235 2/20 0.47
▸ GAA P10253 2/20 0.47
▸ AAK1 Q2M2I8 4/20 0.46
▸ EPHX1 P07099 2/20 0.46
▸ HDAC4 P56524 1/20 0.45
▸ HDAC1 Q13547 1/20 0.45
▸ HDAC6 Q9UBN7 1/20 0.45
▸ BTK Q06187 1/20 0.44
▸ KMT2A Q03164 2/20 0.40
▸ CTSL P07711 1/20 0.39
▸ CA1 P00915 1/20 0.38
▸ CA2 P00918 1/20 0.38
▸ CA7 P43166 1/20 0.38
▸ MMP1 P03956 1/20 0.38
▸ MMP2 P08253 1/20 0.38
▸ MMP3 P08254 1/20 0.38
▸ MMP7 P09237 1/20 0.38
▸ MMP13 P45452 1/20 0.38
▸ MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL844823 1.00 CTSS (0.47) CTSSCTSKGAAAAK1EPHX1
SCHEMBL127389 1.00 CTSS (0.47) CTSSCTSKGAAAAK1EPHX1
SCHEMBL844822 1.00 CTSS (0.47) CTSSCTSKGAAAAK1EPHX1
SCHEMBL22285128 1.00 CTSS (0.47) CTSSCTSKGAAAAK1EPHX1
SCHEMBL22125910 1.00 CTSS (0.47) CTSSCTSKGAAAAK1EPHX1
SCHEMBL23005710 1.00 CTSS (0.47) CTSSCTSKGAAAAK1EPHX1
SCHEMBL29048029 0.98 CTSS (0.46) CTSSCTSKGAAAAK1EPHX1
Lithium SCHEMBL30468513 0.98 CTSS (0.46) CTSSCTSKGAAAAK1EPHX1
SCHEMBL464205 0.98 AAK1 (0.47) CTSSCTSKGAAAAK1EPHX1
SCHEMBL6820204 0.98 AAK1 (0.47) CTSSCTSKGAAAAK1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421212-B2 Substituted benzenecarboxamides as IL-17A modulators DICE ALPHA, INC. (US) 2025-09-23 — — US disclosed
US-12234225-B2 IL-17 ligands and uses thereof DICE ALPHA, INC. (US) 2025-02-25 — — US disclosed
US-20250011303-A1 SMALL MOLECULE MODULATORS OF IL-17A, METHODS OF MAKING AND METHODS OF USING THEREOF ASCLETIS PHARMA (CHINA) CO., LIMITED (CN) 2025-01-09 — — US disclosed
CN-117957212-A IL-17A modulators based on phenylacetamide and uses thereof 戴斯阿尔法公司 2024-04-30 — — CN disclosed
WO-2023225664-A1 LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. (US) 2023-11-23 — — WO disclosed
CN-116547275-A IL-17A modulators 赛诺菲 2023-08-04 — — CN disclosed
CN-116323596-A Interleukin-17 inhibitors 诺华股份有限公司 2023-06-23 — — CN disclosed
US-20230145481-A1 SUBSTITUTED BENZENECARBOXAMIDES AS IL-17A MODULATORS DICE ALPHA, INC. 2023-05-11 — — US disclosed
US-20230145481-A1 SUBSTITUTED BENZENECARBOXAMIDES AS IL-17A MODULATORS DICE ALPHA, INC. 2023-05-11 — — US disclosed
WO-2023078319-A1 HETEROCYCLIC COMPOUND CAPABLE OF INHIBITING IL-17A AND USE OF HETEROCYCLIC COMPOUND 海思科医药集团股份有限公司 2023-05-11 — — WO disclosed
CN-113874080-A IL-17A modulators and uses thereof 戴斯阿尔法公司 2021-12-31 — — CN disclosed
EP-3921038-A1 IL-17A MODULATORS AND USES THEREOF Dice Alpha, Inc. (US) 2021-12-15 — — EP disclosed
US-20210101886-A1 IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. 2021-04-08 — — US disclosed
US-20210101886-A1 IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. 2021-04-08 — — US disclosed
WO-2021055376-A1 IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. (US) 2021-03-25 — — WO disclosed
WO-2021055376-A1 IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. (US) 2021-03-25 — — WO disclosed
WO-2020163554-A1 IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. (US) 2020-08-13 — — WO disclosed
WO-2020163554-A1 IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. (US) 2020-08-13 — — WO disclosed
US-20200247785-A1 IL-17 Ligands And Uses Thereof DICE MOLECULES SV, INC. 2020-08-06 — — US disclosed
US-20200247785-A1 IL-17 Ligands And Uses Thereof DICE MOLECULES SV, INC. 2020-08-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230145481-A1 SUBSTITUTED BENZENECARBOXAMIDES AS IL-17A MODULATORS IL17A, IL2, IL23R CTSS 2035/4885CTSK 2094/4885GAA 2965/4885
US-20200247785-A1 IL-17 Ligands And Uses Thereof IL17A, IL2, IL15 CTSS 1864/4885CTSK 1100/4885GAA 3445/4885
US-12234225-B2 IL-17 ligands and uses thereof IL17A, IL2, IL15 CTSS 1864/4885CTSK 1100/4885GAA 3445/4885
US-12421212-B2 Substituted benzenecarboxamides as IL-17A modulators IL17A, IL2, IL23R CTSS 2092/4885CTSK 2142/4885GAA 2937/4885
US-20250011303-A1 SMALL MOLECULE MODULATORS OF IL-17A, METHODS OF MAKING AND METHODS OF USING THEREOF IL17A, IL15, IL23R CTSS 607/4885CTSK 601/4885GAA 2376/4885
US-20210101886-A1 IL-17A MODULATORS AND USES THEREOF IL17A, IL2, IL36G CTSS 1441/4885CTSK 571/4885GAA 1944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.