⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1899759 | 0.79 | ALDH1A1 (0.47) | — | |
| SCHEMBL14842937 | 0.79 | ALDH1A1 (0.47) | — | |
| SCHEMBL10017905 | 0.78 | — | — | |
| SCHEMBL6654060 | 0.78 | — | — | |
| SCHEMBL2078018 | 0.78 | — | — | |
| SCHEMBL2078020 | 0.78 | — | — | |
| Ethylene SCHEMBL11644945 | 0.73 | ALDH1A1 (0.42) | — | |
| Ethylene SCHEMBL11644957 | 0.73 | ALDH1A1 (0.42) | — | |
| SCHEMBL10500185 | 0.73 | — | — | |
| SCHEMBL819793 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710592-B1 | MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF AMIDES | COLUMBIA S R L (IT) | 2022-08-31 | — | — | EP | disclosed |
| US-11261468-B2 | Microbiological process for the preparation of amides | COLUMBIA SRL (IT) | 2022-03-01 | — | — | US | disclosed |
| EP-3710592-A1 | MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF AMIDES | Columbia S.r.l. (IT) | 2020-09-23 | — | — | EP | disclosed |
| US-20200248216-A1 | MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF AMIDES | COLUMBIA SRL (IT) | 2020-08-06 | — | — | US | disclosed |