SCHEMBL22287239

SCHEMBL22287239

N#CCC1CN1Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.42
SIGMAR1 Q99720 2/20 0.41
FUCA1 P04066 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL122958 0.86 SIGMAR1 (0.54) SIGMAR1
SCHEMBL21315832 0.86 SIGMAR1 (0.54) SIGMAR1
SCHEMBL17154964 0.84 GBA1 (0.44) SIGMAR1
SCHEMBL6174995 0.82 SPHK2 (0.48)
SCHEMBL1903624 0.82 SPHK2 (0.48)
SCHEMBL23044929 0.81 ALDH1A1 (0.41) SIGMAR1
SCHEMBL23044928 0.81 ALDH1A1 (0.41) SIGMAR1
SCHEMBL1257677 0.80 SLC6A4 (0.49)
SCHEMBL1257675 0.80 SLC6A4 (0.49)
SCHEMBL28360256 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3710592-B1 MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF AMIDES COLUMBIA S R L (IT) 2022-08-31 EP disclosed
US-11261468-B2 Microbiological process for the preparation of amides COLUMBIA SRL (IT) 2022-03-01 US disclosed
US-20200248216-A1 MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF AMIDES COLUMBIA SRL (IT) 2020-08-06 US disclosed
US-20200248216-A1 MICROBIOLOGICAL PROCESS FOR THE PREPARATION OF AMIDES COLUMBIA SRL (IT) 2020-08-06 US disclosed