SCHEMBL22288152

SCHEMBL22288152

CSc1cnc2ccccc2c1SC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.45
GPR3 P46089 1/20 0.45
CYP2C19 P33261 2/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP1A2 P05177 2/20 0.40
PPARG P37231 1/20 0.40
NCOA2 Q15596 1/20 0.40
NCOA1 Q15788 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HTT P42858 1/20 0.40
CYP2D6 P10635 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
PDPK1 O15530 2/20 0.37
CA12 O43570 1/20 0.37
PARP1 P09874 1/20 0.37
ALOX15 P16050 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25203412 0.82 KDM4E (0.40) KDM4EGPR3CYP2C19ALDH1A1CYP1A2
SCHEMBL10424115 0.81 NCF1 (0.46) KDM4EGPR3CYP2C19ALDH1A1CYP1A2
Hydrochloric Acid SCHEMBL10424108 0.79 NCF1 (0.44) KDM4EGPR3CYP2C19ALDH1A1CYP1A2
SCHEMBL29661833 0.77 MAPT (0.54) KDM4EALDH1A1CYP1A2NCOA1SMN1; SMN2
SCHEMBL22288125 0.77 MAPT (0.54) KDM4EALDH1A1CYP1A2NCOA1SMN1; SMN2
SCHEMBL25235741 0.74 KDM4E (0.40) KDM4EGPR3CYP2C19CYP1A2SMN1; SMN2
SCHEMBL17423359 0.74 KDM4E (0.50) KDM4EGPR3CYP2C19ALDH1A1CYP1A2
SCHEMBL7053633 0.73 NCF1 (0.50) KDM4ECYP2C19ALDH1A1CYP1A2SMN1; SMN2
SCHEMBL30726252 0.73 KDM4E (0.36) KDM4EGPR3CYP2C19CYP1A2SMN1; SMN2
SCHEMBL10423535 0.72 KMT2A (0.52) KDM4ECYP2C19ALDH1A1NPSR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111517902-B Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2022-06-14 CN disclosed
CN-111517902-A Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2020-08-11 CN disclosed
WO-2020155595-A1 AEROBIC OXIDATION SYSTEM CONTAINING SULFINIC ACID, SULFONIC ACID OR DERIVATIVES THEREOF AND PHOTOCATALYTIC OXIDATION METHOD THEREFOR 清华大学 2020-08-06 WO disclosed